Memory Booster

An implantable device that mimics the electrical brain signals associated with learning and memory has been demonstrated to improve memory performance by up to 25 percent. The approach may have long-term implications for reducing memory loss associated with Alzheimer’s and dementia, as well as enhancing other brain functions.

Twenty volunteers, who were already having electrodes implanted in their brains to treat epilepsy, underwent a procedure to have the new electrodes implanted in the hippocampus region of the brain. Researchers monitored brain activity while the subjects performed a battery of tests to measure short-term and working memory. This data was used to create simulated patterns of brain activity, which were then used to stimulate the brain as the volunteers performed additional tests. One-third received the simulated brain signals, one-third received random signals and one-third received no external stimulation.

According to the results, participants who received the experimental stimulation exhibited a 15 percent improvement in short-term memory and a 25 percent improvement in working memory as compared to those who received no stimulation. Random stimulation actually caused a decrease in performance.

The team believes that a similar approach could be used to improve other skills that are localized to specific regions of the brain, such as sensation, vision and motor skills. However, functions, such as intelligence, which compose many areas of brain activity, would not likely be good candidates for the technique. In separate testing, they are also investigating dangers of the device potentially implanting false memories.

For information: Dong Song, University of Southern California, Viterbi School of Engineering, Corwin D. Denney Research Center, 1042 Downey Way, Los Angeles, CA 90089; phone: 213-740-0839; email: dsong@usc.edu; Web site: https://www.usc.edu/