Malaria Vaccination…for Mosquitoes
It’s been estimated that malaria claims 660,000 lives per year, and that each day, more than 1,400 children die from a mosquito bite – about one per minute. Now biologists have found a novel way of warding off this deadly disease by treating mosquitoes with a vaccine that prevents them from becoming carriers. The trick was finding a way to deliver the vaccine. The answer: Give it to humans.
Malaria is caused by a parasite called Plasmodium which is carried around in the gut of mosquitoes by binding to a protein known as AnAPN1. When you vaccinate people against this protein, they manufacture antibodies which stay in the blood for several years. Any mosquito that bites a vaccinated person ingests the antibodies which, in turn, block the malaria-causing parasite. While this is not a cure for those who are already infected, it represents a crucial step in controlling the spread of the disease.
For information: Rhoel Dinglasan, Johns Hopkins University, Molecular Biology and Immunology, School of Public Health, 615 N. Wolfe Street, E5646, Baltimore, MD 21205; phone: 410-614-4839; email:rdinglas@jhsph.edu; Web site: www.jhu.edu or www.dinglasanlab.org
Malaria No More, 432 Park Ave. South, 4th floor, New York, NY 10016; phone: 212-792-7929; Web site: www.malarianomore.org