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The big ideas that are changing everything

Cancer Imaging Glasses

Up to 25 percent of breast cancer patients end up requiring a second surgery to remove cells that could not be detected the first time around. But a new wearable technology is being developed that would enable surgeons to distinguish cancer cells from healthy ones, reducing the the need for repeat procedures and the associated pain and anxiety.

The tumor can be visualized by first injecting a contrast agent that targets only the cancerous cells. Under a special light, a video camera sends images to a head-mounted display where the targeted cells glow green. In one published study, it was noted that tumors as small as one millimeter could be detected. Theoretically, the technique would be applicable to any type of cancer.

The pilot testing was performed on mice using a common contrast agent called indocyanine green, however, a new agent is being developed for use with the glasses that will stay in the cancer cells longer.

For information: Samuel Achilefu, Washington University School of Medicine, Optical Radiology Lab, Campus Box 8225, 4525 Scott Avenue, St. Louis, MO 63110; phone: 314-362-8599; email: achilefus@mir.wustl.edu; Web site: www.wustl.edu

Daniel Burrus' Top Twenty Technology-Driven Trends for 2014